Thermoplastic elastomers (TPE) is an elastomeric material suitable for use in medical applications due to its inertness, low leachables and biocompatibility. Plasticisers are added into TPE blends to improve its processability ...

Glimepiride, an antidiabetic drug was classified as Class II drug in Biopharmaceutical Classification System (BCS) due to its low solubility (< 0.004 mg/mL) and high permeability. The aim of this work was to investigate ...

Propionibacterium acnes (P. acnes), plays a key role in acne pathogenesis by inducing the innate immune system cells to produce certain pro-inflammatory mediators which contribute to the formation of inflammatory acne ...

Breast cancer is the most common cancer and the leading cause of cancer death among women worldwide. The molecular indication of breast cancer includes physiological abnormalities of cellular components, immunomodulatory ...

The discovery of new therapeutic agents for inflammatory disorders has attracted more attention in recent years. Chalcone term is given to the flavonoid compounds bearing the 1,3-diphenyl-2-propen-1-one framework. Generally, ...

Colorectal cancer is a global burden, today. Currently, the drop in the number of drugs approved by FDA and their limited success, enforce medicinal chemists and biotech industries to develop novel drugs to meet the demands ...

A group of benzothiazole-amide derivatives (VH01-06) were conventionally synthesised in using modified reaction conditions of the Schotten-Baumann named reaction, all the synthesised compounds were characterised using ...