Breast cancer is one of the most common malignancies in women. It continues to be a major burden and cause of death among women worldwide. Current treatment strategies for metastatic breast cancer (MBC) depend upon patient ...

Background: Mutations in the p53 gene have been observed in approximately 50% of all human cancers. In breast cancer alone, 12%-32% of luminal, 84% of basal-like and 75% of HER-2 expressing tumours have evident p53 ...